Methotrexate
Methotrexate is a medication used primarily for treating severe psoriasis, rheumatoid arthritis, and certain types of cancer.
Impact of Gene Variants
Genetic variations, particularly in the RFC1 and ABCB1 genes, can significantly affect the pharmacokinetics and response to Methotrexate.
Ways to Recognize Problems
Symptoms of Methotrexate-related problems may include nausea, vomiting, heartburn, and feeling full long after meals.
Ways to Improve
Dosage adjustments based on genetic testing and maintaining a healthy lifestyle can improve the effectiveness of Methotrexate.
Did you know
Methotrexate has been used for more than two decades to treat juvenile idiopathic arthritis (JIA) and is the most commonly prescribed DMARD for JIA.
