RFC1

Description

The RFC1 gene, also known as Replication Factor C subunit 1, plays a crucial role in DNA replication and repair. It encodes a protein that is part of a complex involved in the unwinding of DNA during replication. RFC1 is essential for the proper function of immune cells, particularly T cells and B cells. Mutations in the RFC1 gene can lead to various immune system disorders and increased susceptibility to infections.

Associated Diseases

• Severe combined immunodeficiency (SCID)
• Ataxia-telangiectasia
• Bloom syndrome
• Fanconi anemia

Did you know?

RFC1 is highly conserved across species, indicating its fundamental importance in cellular processes.