ZSWIM7
Description
The ZSWIM7 (zinc finger SWIM-type containing 7) is a protein-coding gene located on chromosome 17.
ZSWIM7 plays a crucial role in the initial steps of homologous recombination repair (HRR), a process that fixes double-stranded DNA breaks that occur during DNA replication or due to DNA damage. This repair pathway is essential for maintaining genomic integrity. ZSWIM7 is also critical for meiotic progression, which is necessary for fertility. These functions are supported by various studies, including those published in PubMed (PMID: 16710300, PMID: 21965664, PMID: 32719396, PMID: 33713115, PMID: 34402903).
ZSWIM7 is also known as ODG10, SPGF71, SWS1.
