ZNF37BP
Description
The ZNF37BP (zinc finger protein 37B, pseudogene) is a pseudo gene located on chromosome 10.
ZNF37BP, also known as ZNF37B or RNF4, is a protein encoded by the ZNF37BP gene in humans. It is a member of the RING finger family of proteins and functions as an E3 ubiquitin ligase. ZNF37BP is involved in various cellular processes, including DNA repair, signal transduction, and transcription. It has been shown to interact with a number of proteins, including the tumor suppressor p53, the DNA repair protein BRCA1, and the transcription factor NF-κB.
The zinc finger protein 37B (ZNF37BP) is an essential component of the SUMOylation pathway, a critical post-translational modification process that regulates protein function. It acts as an E3 ligase, specifically targeting proteins for SUMO conjugation. ZNF37BP is involved in various cellular processes, including DNA repair, signal transduction, and transcription. Its dysregulation can lead to disruptions in these processes, potentially contributing to disease development.
ZNF37BP is also known as KOX21, ZNF37B.
