ZMYM2 : zinc finger MYM-type containing 2
Description
The ZMYM2 (zinc finger MYM-type containing 2) is a protein-coding gene located on chromosome 13.
The ZMYM2 gene provides instructions for making a protein whose function is not completely understood. It belongs to a family of zinc finger proteins, which have short regions called zinc finger domains. These domains in the ZMYM2 protein are thought to help it control interactions with other proteins. Found in the nucleus of the cell, ZMYM2 likely associates with other proteins. Through these associations, the ZMYM2 protein might be involved in fixing DNA errors, controlling gene activity, or forming structures in the nucleus called PML nuclear bodies that stop cell growth and division and encourage cell death (apoptosis).
ZMYM2 is also known as FIM, MYM, NECRC, RAMP, SCLL, ZNF198.
Associated Diseases
- Neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities
- 8p11 myeloproliferative syndrome
