XRCC3
Description
The XRCC3 gene provides instructions for creating a protein that plays a critical role in DNA repair, specifically in the process of homologous recombination. This process uses an undamaged DNA strand as a template to repair breaks in a damaged strand, ensuring the integrity of the genetic code. XRCC3 protein teams up with another protein, RAD51, to form a complex that searches for and binds to homologous DNA sequences. This complex then helps to align the damaged and undamaged DNA strands, facilitating the repair process. Proper functioning of XRCC3 is essential for maintaining genomic stability and preventing the accumulation of mutations that can lead to cancer and other diseases.
Associated Diseases
Did you know?
Mutations in the XRCC3 gene are associated with an increased risk of developing certain types of cancer, particularly those related to DNA damage.
