WDR92
Introducing the wdr92 Gene: A Guardian of Cellular Vitality and Health
Description
The wdr92 gene, located on chromosome 12, holds a critical role in maintaining cellular homeostasis and preventing disease. It encodes a protein known as WD repeat-containing protein 92, which participates in a variety of cellular processes, including:
- DNA damage repair
- Transcription regulation
- Protein translation
- Cell cycle progression
Associated Diseases
Mutations in the wdr92 gene have been linked to several diseases, including:
- Diamond-Blackfan Anemia (DBA): A rare congenital disorder characterized by impaired red blood cell production, leading to anemia.
- Myelodysplastic Syndrome (MDS): A group of blood disorders affecting the production of blood cells.
- Acute Myeloid Leukemia (AML): A type of cancer that affects the blood-forming cells in the bone marrow.
- Pancreatic Cancer: A deadly malignancy of the pancreas.
Did you Know ?
According to the National Institutes of Health (NIH), mutations in the wdr92 gene are found in approximately 25% of DBA patients and 2-5% of MDS patients.
