VKORC1
Description
The VKORC1 gene provides instructions for making an enzyme called vitamin K epoxide reductase complex subunit 1. This enzyme plays a crucial role in the activation of vitamin K, a nutrient essential for blood clotting. Vitamin K is necessary for the synthesis of several proteins involved in coagulation, including prothrombin. VKORC1 converts vitamin K epoxide to its active form, vitamin K hydroquinone, allowing it to participate in the carboxylation of clotting factors. This process is critical for proper blood clotting and preventing excessive bleeding.
Associated Diseases
Did you know?
Variations in the VKORC1 gene can influence a person‘s sensitivity to warfarin, a blood-thinning medication.