VANGL2


Description

The VANGL2 (VANGL planar cell polarity protein 2) is a protein-coding gene located on chromosome 1.

VANGL2 planar cell polarity protein 2 is a protein that in humans is encoded by the VANGL2 gene. The protein encoded by the VANGL2 gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

VANGL2 is also known as LPP1, LTAP, STB1, STBM, STBM1.

Associated Diseases


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