UTP20


Description

The UTP20 (UTP20 small subunit processome component) is a protein-coding gene located on chromosome 12.

UTP20, also known as Small subunit processome component 20 homolog, is a protein encoded by the UTP20 gene in humans.

UTP20 is a component of the small subunit (SSU) processome, which is the initial precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, UTP20, along with numerous ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins, interacts with the newly formed pre-rRNA. This complex works together to ensure proper RNA folding, modifications, rearrangements, and cleavage, as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. UTP20 is crucial for the processing of 18S pre-rRNA and associates with U3 snoRNA.

UTP20 is also known as 1A6/DRIM, DRIM.

Associated Diseases



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