UTP18
Description
The UTP18 (UTP18 small subunit processome component) is a protein-coding gene located on chromosome 17.
UTP18, also known as U3 small nucleolar RNA-associated protein 18 homolog, is a protein encoded by the UTP18 gene in humans.
UTP18 is a component of the small subunit (SSU) processome, which is the initial precursor of the small eukaryotic ribosomal subunit. Within the nucleolus, the SSU processome assembles and various ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins interact with the nascent pre-rRNA. This collaborative effort results in RNA folding, modifications, rearrangements, cleavage, and the targeted degradation of pre-ribosomal RNA by the RNA exosome. UTP18 plays a crucial role in the nucleolar processing of pre-18S ribosomal RNA.
UTP18 is also known as CGI-48, WDR50.
