USP48
Description
The USP48 (ubiquitin specific peptidase 48) is a protein-coding gene located on chromosome 1.
USP48 is a human gene that encodes a deubiquitinating enzyme, also known as a ubiquitin carboxyl-terminal hydrolase. This enzyme is involved in the removal of ubiquitin from proteins, a process known as deubiquitination. Deubiquitinating enzymes play crucial roles in various cellular processes, including protein degradation, signal transduction, and DNA repair. USP48 is known to be involved in the processing of poly-ubiquitin precursors, as well as that of ubiquitinated proteins. The gene has multiple splice variants, resulting in different protein isoforms.
USP48 is a deubiquitinase that removes ubiquitin from proteins. It is involved in the processing of polyubiquitin precursors and ubiquitinated proteins. USP48 may regulate NF-κB activation by interacting with RELA and TRAF2. It may also play a role at postsynaptic sites.
USP48 is also known as DFNA85, RAP1GA1, USP31.
