USP31

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Description

The USP31 (ubiquitin specific peptidase 31) is a protein-coding gene located on chromosome 16.

USP31 can break down ubiquitin chains by cleaving the bond between the last ubiquitin molecule and the protein it's attached to. This process is essential for regulating the levels of ubiquitinated proteins in the cell.

USP31 is also known as -.

Associated Diseases

• spinocerebellar ataxia type 12
• X-linked spinocerebellar ataxia type 4
• neuroferritinopathy
• hypermanganesemia with dystonia 2
• leukoencephalopathy with calcifications and cysts
• spinocerebellar ataxia type 20
• spastic ataxia 2
• corticobasal syndrome
• infantile-onset generalized dyskinesia with orofacial involvement
• X-linked parkinsonism-spasticity syndrome
• Huntington disease-like syndrome due to C9ORF72 expansions