UGT2B17


Description

The UGT2B17 (UDP glucuronosyltransferase family 2 member B17) is a protein-coding gene located on chromosome 4.

UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene.

UDP-glucuronosyltransferase (UGT) catalyzes phase II biotransformation reactions, conjugating lipophilic substrates with glucuronic acid to enhance water solubility, thus facilitating excretion through urine or bile. This enzyme specifically glucuronidates endogenous steroid hormones, including androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol).

UGT2B17 is also known as BMND12, UDPGT2B17.

Associated Diseases


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