TUBAL3
Description
The TUBAL3 (tubulin alpha like 3) is a protein-coding gene located on chromosome 10.
TUBAL3, a protein similar to alpha-tubulin, likely contributes to the formation of microtubules. These structures are essential for various cellular processes, including cell division, intracellular transport, and maintaining cell shape. TUBAL3 might play a role in adding GTP-bound dimers to the growing microtubule end, forming a stabilizing cap. It is also possible that TUBAL3 possesses GTPase activity, similar to alpha-tubulin, which would contribute to the GDP-bound state of dimers below the cap.
TUBAL3 is also known as -.
Associated Diseases
- esophageal cancer
- schizophrenia 15
- 22q11.2 deletion syndrome
- Phelan-McDermid syndrome
- hypoparathyroidism, familial isolated, 2
- Potocki-Lupski syndrome
