TSPAN6
Description
The TSPAN6 (tetraspanin 6) is a protein-coding gene located on chromosome X.
TSPAN6 is a gene that encodes a protein called Tetraspanin-6. This protein belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins are characterized by four hydrophobic domains and reside on the cell surface. They play a crucial role in mediating signal transduction events, influencing cell development, activation, growth, and motility. TSPAN6 is a cell surface glycoprotein that shares a high degree of similarity with the transmembrane 4 superfamily member 2. The gene utilizes alternate polyadenylation sites, allowing for the production of various mRNA transcripts.
TSPAN6 plays a critical role in cell development, activation, growth, and motility. It is involved in signal transduction events, influencing cellular processes by mediating interactions between cells and their environment.
TSPAN6 is also known as T245, TM4SF6, TSPAN-6.
Associated Diseases
- 7q11.23 microduplication syndrome
- microangiopathy and leukoencephalopathy, pontine, autosomal dominant
- cancer
- glioblastoma
