TSPAN3


Description

The TSPAN3 (tetraspanin 3) is a protein-coding gene located on chromosome 15.

Tetraspanin-3 is a protein encoded by the TSPAN3 gene in humans. It belongs to the transmembrane 4 superfamily (tetraspanin family), known for their cell-surface localization and four hydrophobic domains. These proteins mediate signal transduction events involved in regulating cell development, activation, growth, and motility. The TSPAN3 gene utilizes alternate polyadenylation sites, resulting in two alternative transcripts encoding different isoforms.

TSPAN3 is also known as TM4-A, TM4SF8, TSPAN-3.

Associated Diseases



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