Triglycerides
Triglycerides are a type of fat found in the blood that can increase the risk of cardiovascular disease and other health issues when elevated.
Impact of Gene Variants
Genetic factors can predispose individuals to high triglyceride levels. Mutations in genes involved in lipid metabolism, such as APOC3 and LPL, can affect triglyceride synthesis, transport, and clearance. Family history of hypertriglyceridemia or lipid disorders increases the likelihood of inheriting genetic susceptibility.
Ways to Recognize Problems
Routine blood tests, including lipid panels, measure triglyceride levels. Elevated triglycerides often present with other lipid abnormalities such as high cholesterol levels. Symptoms of severe hypertriglyceridemia may include abdominal pain, pancreatitis, and eruptive xanthomas (yellowish skin lesions).
Ways to Improve
Lifestyle modifications play a crucial role in managing triglyceride levels. Adopting a heart-healthy diet low in saturated fats, trans fats, and sugars while high in fiber-rich foods, fruits, vegetables, and omega-3 fatty acids can help lower triglycerides. Regular physical activity, weight management, smoking cessation, and limiting alcohol intake also contribute to triglyceride reduction. Medications such as statins, fibrates, or omega-3 fatty acid supplements may be prescribed for individuals with persistently high triglycerides despite lifestyle changes.
Did you know
More than 25% of U.S. adults have high triglyceride levels.
