TRAPPC2B

---

Description

The TRAPPC2B (trafficking protein particle complex subunit 2B) is a protein-coding gene located on chromosome 19.

TRAPPC2B, also known as MBP-1-interacting protein 2A, prevents the transcriptional repression and induction of cell death caused by ENO1. It may also play a role in the movement of vesicles from the endoplasmic reticulum to the Golgi apparatus.

TRAPPC2B is also known as MIP-2A, MIP2A, SEDLP, SEDLP1, TRAPPC2P1.

Associated Diseases

• snowflake vitreoretinal degeneration
• corneal endothelial dystrophy
• megalocornea
• keratoconus
• keratoconus 1
• 46,XX ovotesticular disorder of sex development
• macular corneal dystrophy
• Leber congenital amaurosis 8
• 46,XY complete gonadal dysgenesis
• congenital stromal corneal dystrophy
• cornea plana 2
• congenital primary aphakia
• Leber congenital amaurosis
• testicular agenesis
• congenital hereditary endothelial dystrophy of cornea
• EDICT syndrome
• 46,XY sex reversal 3
• refractive error