TOB2

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Description

The TOB2 (transducer of ERBB2, 2) is a protein-coding gene located on chromosome 22.

Protein Tob2 (transducer of ERBB2, 2) is a protein that in humans is encoded by the TOB2 gene. TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression. It has been shown to interact with CNOT7.

TOB2 is also known as APRO5, TOB4, TOBL, TROB2.

Associated Diseases

• asthma
• Kallmann syndrome