TNP1
TNP1 Gene: Unraveling Its Significance in Health and Disease
Description
The TNP1 gene, also known as the transitional nuclear protein 1 gene, plays a vital role in cellular processes. It encodes the TNP1 protein, which is involved in transcription, translation, and mRNA splicing. TNP1 is found within the nucleus of cells and is essential for the proper functioning of the cell cycle.
Associated Diseases
Mutations or alterations in the TNP1 gene have been linked to various health conditions, including:
- Intellectual disability: Specific mutations in TNP1 are associated with intellectual disability, characterized by impaired cognitive development and difficulty with daily living skills.
- Neurodevelopmental disorders: TNP1 mutations have been implicated in neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD).
- Cancer: Overexpression of TNP1 has been observed in certain types of cancer, such as breast cancer and leukemia.
Did you Know ?
- According to the National Institutes of Health (NIH), approximately 1 in 100,000 individuals are affected by TNP1-related intellectual disability.
