TNNI3

The TNNI3 gene builds cardiac troponin I, a protein essential for heart muscle contractions. TNNI3 helps regulate the interaction between muscle components, allowing the heart to beat. Mutations in TNNI3 are linked to familial hypertrophic cardiomyopathy (HCM), a condition where the heart muscle abnormally thickens.

Associated Diseases

Familial Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy 2A

Did you know

HCM can sometimes be present with no symptoms, but it‘s important to get checked if there‘s a family history, as early detection can help manage the condition and potentially prevent complications. HCM affects about 1 in 500 individuals.