TNFAIP3


Description

TNFAIP3, also known as A20, is a crucial gene involved in the regulation of immune responses. It encodes a protein that acts as a negative regulator of NF-κB signaling pathway, a key pathway in inflammation and immunity. This gene‘s primary function is to prevent excessive inflammation by inhibiting the production of pro-inflammatory cytokines. TNFAIP3 plays a vital role in maintaining immune homeostasis and preventing autoimmune diseases.

Associated Diseases

Did you know?

Mutations in the TNFAIP3 gene can lead to severe immune dysregulation and increased susceptibility to autoimmune diseases.


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