TMSB4Y

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Description

The TMSB4Y (thymosin beta 4 Y-linked) is a protein-coding gene located on chromosome Y.

Thymosin beta-4, Y-chromosomal is a protein encoded by the TMSB4Y gene on the Y chromosome. It consists of 44 amino acids with a molecular weight of 4881. This gene resides within the male-specific region of the Y chromosome. Interestingly, its homolog on the X chromosome (thymosin beta-4) escapes X inactivation and also encodes an actin sequestering protein.

TMSB4Y is also known as TB4Y.

Associated Diseases

• factor VII deficiency
• congenital factor X deficiency
• left ventricular noncompaction
• hemophilia A
• aneurysm, intracranial berry, 12
• congenital factor V deficiency
• factor X deficiency
• congenital afibrinogenemia
• congenital factor XIII deficiency
• moderately severe hemophilia A
• congenital plasminogen activator inhibitor type 1 deficiency
• cardiomyopathy, dilated, 2G
• factor XIII, A subunit, deficiency of
• severe hemophilia A
• hemophilia B
• cerebral amyloid angiopathy, APP-related
• familial cervical artery dissection
• left ventricular noncompaction 10
• congenital factor VII deficiency