TMEM44
Description
The TMEM44 (transmembrane protein 44) is a protein-coding gene located on chromosome 3.
TMEM44 (Transmembrane protein 44) is a protein that in humans is encoded by the TMEM44 gene. DKFZp686O18124 is a synonym of TMEM44.
== Gene == TMEM44 gene has 14 transcripts (splice variants). The whole span of the gene is 46,016 base pairs long, while the mRNA sequence of TMEM44 is 1,483 base pairs long, with 13 exons. Exon 1 and 2 partial are part of 5'-UTR, and the partial exon 2 is only highly conserved in primates.
=== Regulation === There are 5 experimentally verified promoters, and 4 predicted ones. Promoter GXP_232172, which is promoter set 5 is the longest with 1,276 base pairs and a total of 11 coding transcripts.
=== Expression === There is an overall low level expression of TMEM44 gene throughout the body parts and throughout the developmental stages of humans. Some parts where TMEM44 expression is detected are in bone, brain, eye, ovary, pancreas and uterus. Some expression was also detected under certain health conditions including gastrointestinal tumor, glioma, ovarian tumor, pancreatic tumor, muscle tissue tumor and uterine tumor.
TMEM44, also known as DKFZp686O18124, is a gene with 14 transcripts, spanning 46,016 base pairs. It produces a 1,483 base pair mRNA sequence with 13 exons. The gene is regulated by 5 experimentally verified promoters and 4 predicted ones, with the longest promoter being 1,276 base pairs and producing 11 coding transcripts. TMEM44 expression is generally low across human body parts and developmental stages, with detectable levels in bone, brain, eye, ovary, pancreas, and uterus. Elevated expression has also been observed in certain tumor types, including gastrointestinal, glioma, ovarian, pancreatic, muscle tissue, and uterine tumors.
TMEM44 is also known as -.
