THRSP
Description
The THRSP (thyroid hormone responsive) is a protein-coding gene located on chromosome 11.
The THRSP gene encodes a protein known as Thyroid hormone-inducible hepatic protein. This protein is similar to the product of the S14 gene in rats, whose expression is limited to the liver and adipose tissue and is regulated by nutritional and hormonal factors. THRSP is expressed in the liver and adipocytes, particularly in lipomatous modules. It's also found in lipogenic breast cancers, suggesting a role in controlling tumor lipid metabolism. Interestingly, THRSP was among the upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats exhibiting inattention behavior.
THRSP is also known as LPGP1, Lpgp, S14, SPOT14, THRP.
