THEG5
The G5 Gene: Unlocking the Secrets of Growth and Health
Description
The G5 gene, formally known as SRD5A3, is located on chromosome 4 and encodes for the enzyme steroid-5-alpha-reductase type 3. This enzyme plays a crucial role in the synthesis of testosterone, a hormone essential for male development and function.
Associated Diseases
Mutations in the G5 gene have been linked to several disorders, including:
- 5α-Reductase Deficiency Type 3: A rare genetic condition characterized by male infertility and incomplete masculinization.
- Benign Prostatic Hyperplasia (BPH): A non-cancerous enlargement of the prostate gland.
- Prostate Cancer: The most common cancer among men in the United States.
Did you Know ?
- Approximately 1 in 100,000 men are affected by 5α-reductase deficiency type 3, making it a rare disorder.
