TATDN1
Description
The TATDN1 (TatD DNase domain containing 1) is a protein-coding gene located on chromosome 8.
TATDN1 is a deoxyribonuclease that catalyzes the unlinking of circular DNA molecules called kinetoplast DNA. This activity is crucial for chromosome separation and cell cycle progression during eye development.
TATDN1 is also known as CDA11.
Associated Diseases
- lysosomal storage disease
- preterm premature rupture of the membranes
- cancer
- mitochondrial complex I deficiency