TAS2R16
Description
The TAS2R16 (taste 2 receptor member 16) is a protein-coding gene located on chromosome 7.
TAS2R16 (taste receptor, type 2, member 16) is a bitter taste receptor that is part of the 25-member TAS2R family, which belong to the G-protein-coupled receptors (GPCRs) family. These receptors detect and are stimulated by various bitter substances found in nature. TAS2R16 is primarily expressed in taste buds located on the surface of the tongue and palate epithelium. This receptor is activated by bitter β-glucopyranosides, such as salicin. The TAS2R16 gene is located on the long arm (q) of chromosome 7 at position 31.1-31.3, spanning 997 bases. This gene is specifically expressed by taste receptor cells of the tongue and palate epithelia. Variations in the TAS2R16 gene can affect an individual's sensitivity to or preference for certain bitter compounds. TAS2R16 consists of 291 amino acids with a molecular weight of 33,986 Da. It has 7 transmembrane helices, 3 intracellular loops, and 3 extracellular loops.
TAS2R16 is also known as BGLPT, T2R16.
