SYT10
Description
The SYT10 (synaptotagmin 10) is a protein-coding gene located on chromosome 12.
SYT10 acts as a calcium sensor essential for the calcium-dependent release of secretory vesicles containing IGF1 from neurons in the olfactory bulb. This process is crucial for the sense of smell. SYT10 does not participate in the calcium-dependent release of synaptic vesicles. Its mechanism involves calcium and phospholipid binding to the C2 domain, which triggers the binding of the C2 domains to phospholipid membranes and assembled SNARE complexes, ultimately leading to exocytosis.
SYT10 is also known as -.