STX3

Description

The STX3 (syntaxin 3) is a protein-coding gene located on chromosome 11.

Syntaxin 3, also known as STX3, is a protein encoded by the STX3 gene. It is a member of the syntaxin family of cellular receptors for transport vesicles involved in exocytosis in neutrophils. STX3 plays a significant role in neurite growth and is directly targeted by omega-6 arachidonic acid. Mutations in Syntaxin 3 cause Microvillus inclusion disease. STX3 has been shown to interact with SNAP-25, SNAP23, and SNAP29.

Plays a role in docking synaptic vesicles at presynaptic active zones and acts as an apical receptor for membrane fusion of apical vesicles.

STX3 is also known as DIAR12, MVID2, RDMVID, STX3A.

Associated Diseases


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