STX17
Description
The STX17 (syntaxin 17) is a protein-coding gene located on chromosome 9.
Syntaxin 17 is a protein encoded by the STX17 gene in humans. A duplication in intron 6 of this gene in horses is linked to progressive graying.
STX17 is a SNARE protein that plays a crucial role in membrane fusion within cells. It is involved in autophagy, a process that helps break down and recycle cellular components, by controlling the fusion of autophagosomes with lysosomes. STX17 also appears to be involved in the early secretory pathway, where it may help maintain the structure of the endoplasmic reticulum-Golgi intermediate compartment and Golgi and regulate the movement of materials between these cellular compartments.
STX17 is also known as -.
Associated Diseases
- benign adult familial myoclonic epilepsy
- breast cancer
- retinoblastoma
- persistent truncus arteriosus
- Dravet syndrome