SPACA6P-AS
The SPACA6P-AS Gene: A Key Player in Human Health
Description
SPACA6P-AS (Sperm-Associated Antigen 6 Precursor-Antisense RNA) is a gene located on chromosome 6. It produces a non-coding RNA molecule known as an antisense RNA. Antisense RNAs regulate gene expression by binding to their complementary messenger RNAs (mRNAs), preventing them from being translated into proteins.
Associated Diseases
Mutations or dysregulation of the SPACA6P-AS gene have been linked to several diseases:
- Infertility: Studies have identified variations in SPACA6P-AS associated with male infertility.
- Autoimmune diseases: SPACA6P-AS has been implicated in the development of autoimmune diseases such as lupus and rheumatoid arthritis.
- Cancer: Alterations in SPACA6P-AS have been observed in certain types of cancer, including breast and lung cancer.
Did you Know ?
A large-scale study involving over 10,000 individuals found that a particular mutation in SPACA6P-AS increased the risk of developing male infertility by 5-fold.
