SNAPC5
Description
The SNAPC5 (small nuclear RNA activating complex polypeptide 5) is a protein-coding gene located on chromosome 15.
SNAPC5, encoded by the SNAPC5 gene, is a protein involved in the snRNA-activating protein complex. This complex is essential for the transcription of both RNA polymerase II and III snRNA genes.
SNAPC5 plays a crucial role in the transcription of both RNA polymerase II and III small-nuclear RNA (snRNA) genes. It binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these snRNA genes. This binding facilitates the recruitment of TBP and BRF2 to the U6 snRNA TATA box, ultimately promoting transcription.
SNAPC5 is also known as SNAP19.
