SMG1P7
Description
The SMG1P7 (SMG1 pseudogene 7) is a pseudo gene located on chromosome 16.
SMG1P7, also known as UPF1, is a protein that is involved in the nonsense-mediated mRNA decay (NMD) pathway. NMD is a cellular surveillance pathway that degrades mRNAs containing premature termination codons (PTCs). This process ensures that only properly processed and functional mRNAs are translated into proteins. SMG1P7 is a key regulator of NMD. It binds to mRNAs containing PTCs and initiates their degradation. This prevents the production of truncated and potentially harmful proteins.
SMG1P7, also known as UPF1, is a vital component of the nonsense-mediated mRNA decay (NMD) pathway. This pathway plays a critical role in eliminating aberrant mRNAs containing premature termination codons (PTCs). SMG1P7 acts as a key regulator of this process, ensuring that only properly processed and functional mRNAs are translated into proteins. It achieves this by recognizing and binding to the mRNAs containing PTCs, leading to their degradation. This mechanism safeguards the cell from producing truncated and potentially harmful proteins.
SMG1P7 is also known as -.
