SLC30A4
Description
The SLC30A4 (solute carrier family 30 member 4) is a protein-coding gene located on chromosome 15.
Zinc transporter 4 is a protein encoded by the SLC30A4 gene in humans.
SLC30A4 is a probable proton-coupled zinc ion antiporter that facilitates the movement of zinc from the cytoplasm into the endocytic compartment (PubMed:19521526). It also plays a role in regulating zinc deposition in milk (By similarity).
SLC30A4 is also known as ZNT4, znT-4.
Associated Diseases
- acheiropody
- tibia, hypoplasia or aplasia of, with polydactyly
- acromesomelic dysplasia 2C, Hunter-Thompson type
- Blount disease
- acromesomelic dysplasia 2A
- tibial hemimelia
- syndactyly type 4
- Gollop-Wolfgang complex
- mesomelic dysplasia, Savarirayan type
- laurin-Sandrow syndrome
- Fuhrmann syndrome
- spondyloepimetaphyseal dysplasia, Missouri type
- Osebold-Remondini syndrome
- acromesomelic dysplasia 2B
- chromosome 17P13.3, telomeric, duplication syndrome
- congenital non-bullous ichthyosiform erythroderma
- erythrokeratodermia variabilis
- ectodermal dysplasia-blindness syndrome
- acrorenal syndrome
- isolated dystonia
