SLC16A11
Description
The SLC16A11 (solute carrier family 16 member 11) is a protein-coding gene located on chromosome 17.
Monocarboxylate transporter 11 (MCT 11) is a protein that in humans is encode by the SLC16A11 gene. Variants in this gene are associated with increased body-mass index and type 2 diabetes.
SLC16A11, also known as MCT11, is a proton-linked monocarboxylate transporter. It facilitates the movement of pyruvate across cell membranes. This transport likely plays a role in hepatic lipid metabolism, as increased expression of SLC16A11 leads to higher levels of triacylglycerol (TAG) and alterations in other lipid components.
SLC16A11 is also known as MCT 11, MCT11.
