SGK223
Description
The sgk223 gene, also known as serum/glucocorticoid regulated kinase 223, is located on chromosome 22 and encodes a serine/threonine kinase. SGK223 belongs to the AGC family of kinases and is activated by phosphoinositide 3-kinase (PI3K) signaling. SGK223 has been implicated in a variety of cellular processes, including cell growth, differentiation, and metabolism.
Associated Diseases
Mutations in the sgk223 gene have been linked to a number of diseases, including:
- Polycystic ovary syndrome (PCOS): PCOS is a hormonal disorder that affects women of reproductive age. It is characterized by irregular menstrual periods, infertility, and excessive androgen levels. Mutations in the sgk223 gene have been found to be associated with an increased risk of PCOS.
- Insulin resistance: Insulin resistance is a condition in which the body does not respond properly to insulin, a hormone that helps to regulate blood sugar levels. Mutations in the sgk223 gene have been found to be associated with an increased risk of insulin resistance.
- Type 2 diabetes: Type 2 diabetes is a chronic disease that is characterized by high blood sugar levels. Mutations in the sgk223 gene have been found to be associated with an increased risk of type 2 diabetes.
Did you Know ?
Approximately 1 in 100 people have a mutation in the sgk223 gene.
