SERPINA7 : serpin family A member 7
Description
Nestled within our genome lies a crucial gene, SERPINA7, also known as TBG. It orchestrates the production of a vital protein called thyroxine-binding globulin (TBG). This protein acts as a devoted chauffeur in our bloodstream, transporting thyroid hormones to various parts of the body. These hormones, secreted by the thyroid gland, a crucial organ in our neck, play a profound role in shaping our overall well-being. They govern our growth, nurture our brain development, and regulate the pace of chemical reactions within our bodies – a process known as metabolism.
Associated Diseases
TBG levels and functionality can impact various health conditions. Hyperthyroidism, a condition characterized by excessive thyroid hormone production, can arise when TBG levels are low. Conversely, hypothyroidism, a state of insufficient thyroid hormone activity, can develop when TBG levels are elevated. In both scenarios, the delicate balance of thyroid hormones is disrupted, leading to diverse symptoms.
Did you Know ?
Did you know that approximately 99% of thyroid hormones in our bloodstream are bound to TBG? This extraordinary protein plays a critical role in regulating the availability of these hormones to our cells.
