SERF2
Description
The SERF2 (small EDRK-rich factor 2) is a protein-coding gene located on chromosome 15.
Small EDRK-rich factor 2 is a protein encoded by the SERF2 gene in humans. You can find more information about SERF2 on the UCSC Genome Browser, including its gene location and details.
SERF2 positively regulates the aggregation and toxicity of amyloid proteins, such as Huntington's protein (HTT). It promotes conformational changes in these proteins, leading to their compact formation, which precedes the formation of aggregates.
SERF2 is also known as 4F5REL, FAM2C, H4F5REL, HsT17089.
Associated Diseases
- type 2 diabetes mellitus
- cancer
- Parkinson disease
- inborn error of immunity
- nonpapillary renal cell carcinoma
- type 1 diabetes mellitus
- colorectal cancer
