SEPT4-AS1

The sept4-as1 Gene: A Comprehensive Guide

Description

The sept4-as1 gene, also known as SEPT4 Antisense RNA 1, is a long non-coding RNA (lncRNA) located on chromosome 1q22. LncRNAs are non-protein-coding RNA molecules that play crucial roles in gene regulation, development, and disease.

Associated Diseases

Dysregulation of the sept4-as1 gene has been implicated in various diseases, including:

  • Colorectal cancer: Sep4-as1 is overexpressed in colorectal cancer and promotes tumor growth and metastasis.
  • Breast cancer: Sep4-as1 is upregulated in breast cancer and is associated with poor prognosis.
  • Liver cancer: Sep4-as1 is a key regulator of liver cancer cell proliferation and invasion.
  • Renal cell carcinoma: Sep4-as1 is involved in the development and progression of renal cell carcinoma.
  • Neuroblastoma: Sep4-as1 promotes cell proliferation, migration, and angiogenesis in neuroblastoma.

Did you Know ?

According to a recent study, the overexpression of sept4-as1 in colorectal cancer is associated with a significantly shorter overall survival rate. Patients with high sept4-as1 expression had a median survival time of 38.6 months compared to 63.4 months in patients with low sept4-as1 expression.


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Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.