SEMA6C
Description
The SEMA6C (semaphorin 6C) is a protein-coding gene located on chromosome 1.
Semaphorin-6C is a protein in humans encoded by the SEMA6C gene. It belongs to the semaphorin family, which plays a crucial role in cellular responses following CNS injury, potentially contributing to neural regeneration.
Semaphorin-6C exhibits growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. It potentially acts as a stop signal for DRG neurons reaching their target areas, potentially impacting other neurons as well. Furthermore, it may contribute to the maintenance and remodeling of neuronal connections.
SEMA6C is also known as SEMAY, Sema-Y, m-SemaY, m-SemaY2.
Associated Diseases
- cancer
- skin cancer
- Dubin-Johnson syndrome
- hypoplastic pancreas-intestinal atresia-hypoplastic gallbalder syndrome
- schizophrenia
- retinitis pigmentosa 89
- Senior-Boichis syndrome
