SEC22B
Description
The SEC22B (SEC22 homolog B, vesicle trafficking protein) is a protein-coding gene located on chromosome 1.
SEC22B is a protein involved in vesicle trafficking. It belongs to the SEC22 family and is thought to play a role in the movement of proteins between the ER and the Golgi. It interacts with other proteins involved in vesicle trafficking, including SNAREs and the COPII complex. SEC22B is similar to proteins found in mice and hamsters, and multiple polyadenylation sites can be used for its mRNA transcript.
SEC22B plays a crucial role in the movement of vesicles between the endoplasmic reticulum (ER) and the Golgi apparatus. It facilitates the fusion of ER-derived transport vesicles with the Golgi, and also helps with the return of Golgi-derived vesicles back to the ER.
SEC22B is also known as ERS-24, SEC22L1.
Associated Diseases
- cancer
- ovarian cancer
- brain injury
- Aagenaes syndrome
- hyperinsulinemic hypoglycemia, familial, 4
- cystic fibrosis
