SDR16C5
Description
The SDR16C5 (short chain dehydrogenase/reductase family 16C member 5) is a protein-coding gene located on chromosome 8.
SDR16C5 is an oxidoreductase that strongly prefers NAD as a cofactor. It can act in both oxidative and reductive directions. SDR16C5 oxidizes all-trans-retinol to all-trans-retinaldehyde. However, it does not exhibit activity with 11-cis-retinol or 11-cis-retinaldehyde as substrates, regardless of whether NAD(+)/NADH or NADP(+)/NADPH is used as a cofactor.
SDR16C5 is also known as EPHD-2, RDH#2, RDH-E2, RDHE2, retSDR2.
