SCUBE1
Description
The SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1) is a protein-coding gene located on chromosome 22.
SCUBE1 (Signal peptide, CUB domain and EGF like domain containing 1) is a protein encoded by the SCUBE1 gene in humans. It is a cell surface glycoprotein that belongs to the SCUBE family. SCUBE family members have a signal peptide at the beginning, nine EGF-like repeats, and a CUB domain at the end. SCUBE1 is found in platelets and endothelial cells, suggesting a role in vascular biology.
SCUBE1 is a cell-surface protein that may play a key role in vascular biology. It could function as an adhesive molecule, and its fragments in the matrix and bloodstream may be important for this function.
SCUBE1 is also known as -.
Associated Diseases
- Glanzmann thrombasthenia 1
- thrombocytopenia 7
- bleeding disorder, platelet-type, 24
- platelet-type bleeding disorder 18
- Bernard-Soulier syndrome
- platelet-type von Willebrand disease
- platelet-type bleeding disorder 10
- platelet-type bleeding disorder 11
