SCG2
Description
The SCG2 (secretogranin II) is a protein-coding gene located on chromosome 2.
SCG2, also known as secretogranin II (chromogranin C), is a protein encoded by the SCG2 gene in humans. It belongs to the chromogranin/secretogranin family of neuroendocrine secretory proteins. Research in rodents suggests that the full-length protein, secretogranin II, plays a role in packaging or sorting peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exhibits chemotactic effects on specific cell types, and EM66, whose function remains unknown.
Neuroendocrine protein that regulates the biogenesis of secretory granules.
SCG2 is also known as CHGC, EM66, SN, SgII.
