S100A3
Description
The S100A3 (S100 calcium binding protein A3) is a protein-coding gene located on chromosome 1.
S100 calcium-binding protein A3 (S100A3) is a protein encoded by the S100A3 gene in humans. This protein belongs to the S100 family and contains two EF-hand calcium-binding motifs. S100 proteins are found in the cytoplasm and/or nucleus of various cell types and regulate cellular processes such as cell cycle progression and differentiation. The S100 gene family consists of at least 13 members clustered on chromosome 1q21. S100A3 stands out due to its high cysteine content, high zinc affinity, and prominent expression in human hair cuticle. Its exact function remains unclear.
S100A3 is also known as S100E.
Associated Diseases
- prostate cancer
- neutropenia, severe congenital, 9, autosomal dominant
- megalocornea
- aniridia
- isolated ectopia lentis
- in situ carcinoma
