RTP4

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Description

The RTP4 (receptor transporter protein 4) is a protein-coding gene located on chromosome 3.

RTP4 is a human gene that encodes a protein involved in the trafficking and functional expression of certain G-protein coupled receptors (GPCRs). It is known to promote the functional expression of the bitter taste receptor TAS2R16 and the opioid receptor heterodimer OPRD1-OPRM1.

RTP4 is also known as IFRG28, Z3CXXC4.

Associated Diseases

• schizophrenia 15
• Phelan-McDermid syndrome
• thrombocytopenia 4
• platelet-type bleeding disorder 15
• macrothrombocytopenia, isolated, 2, autosomal dominant
• bleeding disorder, platelet-type, 24
• thrombocytopenia 2
• platelet-type bleeding disorder 10
• autosomal dominant macrothrombocytopenia
• Potocki-Lupski syndrome
• DIAPH1-related sensorineural hearing loss-thrombocytopenia syndrome
• beta-thalassemia-X-linked thrombocytopenia syndrome
• systemic lupus erythematosus