RPS17 : ribosomal protein S17
Description
The RPS17 (ribosomal protein S17) is a protein-coding gene located on chromosome 15.
The RPS17 gene provides instructions for making a ribosomal protein, a key component of ribosomes, which are cellular structures responsible for protein synthesis. Ribosomes have two subunits: large and small. RPS17 protein is found in the small subunit. While the exact functions of RPS17 and other ribosomal proteins are not fully understood, some are involved in ribosome assembly and stability, while others contribute to protein synthesis. Some studies suggest that certain ribosomal proteins may participate in cell signaling pathways, cell division regulation, and programmed cell death (apoptosis).
RPS17 is a component of the small ribosomal subunit (SSU), which is a crucial part of the ribosome responsible for protein synthesis. RPS17 is involved in the assembly of the SSU processome, the initial precursor of the small eukaryotic ribosomal subunit. During the assembly process in the nucleolus, RPS17 associates with other ribosome biogenesis factors, an RNA chaperone, and pre-ribosomal RNA. These components work together to achieve proper RNA folding, modifications, rearrangements, and cleavage. The SSU processome also involves targeted degradation of pre-ribosomal RNA by the RNA exosome.
RPS17 is also known as DBA4, RPS17L, RPS17L1, RPS17L2, S17, eS17.
