RPS16
Description
The RPS16 (ribosomal protein S16) is a protein-coding gene located on chromosome 19.
RPS16 (Ribosomal Protein S16) is a gene that encodes a protein involved in protein synthesis. This protein is a component of the small ribosomal subunit (40S), which, along with the large 60S subunit, forms the ribosome, the cellular machinery responsible for protein production. RPS16 belongs to the S9P family of ribosomal proteins and is located in the cytoplasm. There are multiple pseudogenes of this gene dispersed throughout the human genome.
RPS16 is a component of the small ribosomal subunit (40S), which is essential for protein synthesis in the cell. It plays a role in the assembly of the small subunit processome, a precursor of the small eukaryotic ribosomal subunit. During this assembly, RPS16 interacts with other ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins to facilitate RNA folding, modifications, rearrangements, and cleavage. RPS16 also participates in the targeted degradation of pre-ribosomal RNA by the RNA exosome.
RPS16 is also known as S16, uS9.
Associated Diseases
- Duchenne muscular dystrophy
- cystic fibrosis
- COVID-19
- Becker muscular dystrophy
- qualitative or quantitative defects of dystrophin
- aniridia
- hemophilia B
- cystinosis
- hemophilia A
- Alport syndrome
